RESEARCH

Personalized medicines and lower-cost drug development are two of the practical benefits of mapping the 3 billion chemical base pairs in the human genome. The human genome project is just one of the groundbreaking research initiatives that involved researchers from the New York State Center of Excellence in Bioinformatics & Life Sciences (CoE). By merging high-performance computing and high-end visualization with genomics, proteomics and bioimaging, the CoE has created a unique and powerful combination of technologies and research expertise that fosters advancements in science and health care. This approach complements the critical mass of world-class researchers, in both basic and applied sciences, who already provide industry partners with a wide scope of potential new leads, technologies, and discoveries through the CoE's primary research institutions: the University at Buffalo, Roswell Park Cancer Institute and the Hauptman-Woodward Medical Research Institute:

The CoE faculty include over 100 biological, physical and computational scientistsfrom interdisciplinary laboratories involved with the COE's translational research efforts representing broad capabilities and core research groups.

Research Capabilities

  • Bioengineering
  • Bioimaging
  • Bioinformatics
  • Cardiology
  • Disease Modeling
  • Epidemiology
  • Genetics
  • Genomics
  • High Performance Computing
  • Immunotherapy
  • Neurology
  • Oncology
  • Oral Biology
  • Structural Biology
  • Pharmacokinetics & Pharmacodynamics
  • Pharmacology
  • Proteomics

Core Research Groups

  • Cancer Biology
  • Cardiovascular Disease
  • Neurodegenerative Disease
  • Pathogens & Biodefense
  • Translational Pharmacology

Research Highlight

UB, Niagara University, Heart Center of Niagara Collaboration Makes Progress in Project Aimed at Tackling Heart Disease in WNY

6/26/09 - BUFFALO, N.Y. -- A collaboration involving physicians, researchers, graduate students and undergraduate students from three prominent regional institutions is intent on improving heart health in Western New York, an area with a heart disease death rate that is twice the national average.

The collaboration, which took shape in 2005, involves the University at Buffalo, Niagara Falls Memorial Medical Center and Niagara University (NU) ,and converges at The Heart Center of Niagara (HCON), part of Niagara Falls Memorial Medical Center in Niagara County, where rates of cardiovascular disease and mortality from the disease are the greatest in the five-county region.

As their first goal, the parties in this venture established a joint research program to evaluate non-invasive cardiac imaging methods for identifying, tracking and stratifying risk of coronary artery disease (CAD) in the population.

Since the collaboration began, information for more than 4,000 patients has been gathered at the HCON to evaluate the effect of innovative positron emission tomography (PET), which offers a potentially more cost-effective and safer approach to managing CAD than traditional invasive coronary angiography. It is the largest database in the country containing this type of vital information, which will allow some of the most robust research possible to understand the how PET can best be used to improve patient care...[Read On...]



Featured Researcher

Joan Dorn, Ph.D.
Associate Professor
Department of Social and Preventive Medicine
School of Public Health and Health Professions

Dr. Joan Dorn
Dr. Joan Dorn is the lead principle investigator collaborator on the research protocols being conducted.  She completed a post-doctoral fellowship with the American Heart Association. Research Interests: My research interests focus on cardiovascular disease epidemiology (CVD), particularly the role of physical activity in heart disease prevention. Most recently I have developed an ultrasound laboratory to study carotid intima media thickness as a marker of structural sub-clinical CVD and brachial artery reactivity as a marker of functional sub-clinical CVD.

Dorn holds a five-year First Independent Research Support and Transition Award from the National Institutes of Health.


News

Turning Research Into Practicality is Focus of Roswell Park Workshop
11/4/2009 - BUFFALO, NY -- "The daylong 'translational research workshop' brought academics and industry representatives together to tackle the difficulties and opportunities of commercializing medical research..." [Read On...]

UB Engineering Professor Honored at White House
10/08/2009 - WASHINGTON, D.C. - "President Obama honored Takeuchi for inventing the battery that powers many of the world's implanted medical devices, but he just as easily could have lauded her as living proof that the American dream still comes true..." [Read On...]

Life Science Careers Touted: UB leads consortium promoting variety of job possibilities in Western New York
10/6/2009 - BUFFALO, NY -- "A program designed to bring careers in the life sciences within reach of more Western New York job-seekers was rolled out Tuesday by a consortium of agencies and businesses led by two branches of the University at Buffalo.  The program is called iSciWNY... " [Read On...]

Visit the News Archive

 

Events

November 19 - "Vybion: The Successful Morphing of a Contract Research Organization into a Therapeutics Company" featuring Lee Henderson, CEO, Vybion Inc. Click here for more information.

December 10 - "The Passport of a Life Sciences Entrepreneur," featuring Shreefel Mehta, Ph.D., MBA.  Click here for more information. 

To view the complete list of events and event details, please visit our Events page

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